Do you want to travel up north and see Nueva Vizcaya, Isabela, and Cagayan? There are several bus companies that provide transportation services from Metro Manila to as far as Cagayan. These include Victory Liner, Baliwag Transit, Florida, EMC, and Dalin Liner.
I studied and stayed in QC since 2003 but I go home to my province - Cagayan every opportune time allows me to spend time with family. Thus, for frequent trip maker like me I prefer to ride the Victory Liner bus. The Victory Liner company employs experienced drivers who are courteous and ensures safe travel. I wouldn't go into detail like comparing it to other buses.
You can easily access their terminal along EDSA in Kamias, Quezon City. They have daily trips leaving almost every 30 minutes.
The total travel time from Manila to Tuguegarao is about 12 hours. There are three to four stopovers depending on the time of your travel or the bus drivers. Fare ranges from 500 to 700 as stated in their website. However, i think their website is not updated since fares currently range from 600 to 800. (For their daily schedule and fares, you can check this:
http://www.victoryliner.com/tripschedules3.htm)
Both day time and night travel is good at least for me who is used to this long trips. When you travel during day time, you get to see green, green, and green scenery of farmlands that is relaxing to your eyes. On the other hand, night travel has also its advantage - that you sleep during the entire travel and arrive in Tugeugarao as you wake up. For night travelers though, an important thing to bring is a thick jacket or a blanket to cover yourself from extreme cold aircon.
Have a safe trip!
